Carla J. Aldrich, Ph.D.

Associate Professor of Microbiology & Immunology
Indiana University School of Medicine - Evansville
8600 University Boulevard
Evansville, IN 47712, USA

B.S., Oklahoma State University (1977)
Ph.D., Baylor College of Medicine, Houston, TX (1987)

Research Interests


Selected Publications

Reinert, R.B. L. M. Oberle, S.A. Wek, P. Bunpo, X.P. Wang, I. Mileva, L.O. Goodwin, C.J. Aldrich, D.L. Durden, M.A. McNurlan, R.C. Wek, and T.G. Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase. J. Biol. Chem., 281(41):3122-33, 2006.

Hermel, E., A. Hart, H. Acton, C. Kim, M.Wurth, S. Uddin, C. Smith, I. Gunduz, K.F. Lindahl, and C.J. Aldrich. Molecular and cellular analyses of the polymorphism of the MHC class IB molecule Qa1.  Immunogenetics, 56(9):639-649, 2004.

Davies, A.H., S. Ramirez, B. Liang, C.J. Aldrich, F. Lemonnier, H. Jiang, R. Cotter, and M. Soloski. A peptide from heat shock protein 60 is the dominant peptide bound to Qa-1 in the absence of the MHC class Ia leader sequence peptide Qdm. J. Immunol. 170: 5027-5033, 2003.

Chun, T., E. Hermel, H.R. Gaskins, and C.J. Aldrich. Sequence and CTL recognition of the MHC class Ib molecule Qa1 in nonobese diabetic (NOD) mice. Immunogenetics, 53: 506-510, 2001.

Bai, A., C.J. Aldrich, and J. Forman. Factors controlling the trafficking and processing of a leader derived peptide presented by Qa-1. J. Immunol., 165: 7025-7034, 2000

Hermel, E., A. Hart, R. Miller and C.J. Aldrich. CTL and sequence analyses of MHC class IB antigens Qa-1c (H2-T23r) and Qa-1d, (H2-T23f). Immunogenetics, 49: 712-717, 1999.

Chun, T., C.J. Aldrich, M.E. Baldeon, L.V. Kawczynski, M.J. Soloski, and H.R. Gaskins. Constitutive and regulated expression of the class IB molecule Qa-1 in pancreatic b cells. Immunology: 94: 64-71, 1998.

Hermel, E., E. Grigorenko, C.J. Aldrich. Increased class IB antigen display on TAP-2 mutant cells by a mitochondrial function inhibitor. Cellular Immunology: 179: 10-15, 1997.

Soloski, M.J., A. DeCloux, C.J. Aldrich, and J. Forman.  Structural and Functional Characteristics of the Class IB molecule, Qa-1.  Immunological Reviews: 147: 67-89, 1995.

C.J. Aldrich, A. DeCloux, A. S. Woods, R. J. Cotter, M. J. Soloski, and J. Forman.  Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a Class IB antigen. Cell: 79: 649-658, 1994.

Bunpo, P., J.K.Cundiff, R.B, Reinert, R.C. Wek, C.J. Aldrich and T.G. Anthony. The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase. J. Nutr., 140(11):2020-7, 2010.

Kaplan, MH, Cundiff JK, Smith JS, Aldrich CJ. “Anti-STAT6 CTL activity in Stat6-/- mice: A cautionary tale”.  JAK-STAT 2013; 2:e24554.

Aldrich, C.J. and E.A. Armeanu. Flip or Flop? Application of a Flipped Classroom Format to a Medical Microbiology and Immunology Course. IAMSE, meeting abstract, 2015




Indiana University School of Medicine - Evansville | 8600 University Boulevard | Evansville, IN 47712